Peptic ulcer disease is a condition in which there are painful sores or ulcers in the lining of the stomach or the first part of the small intestine (the duodenum). Normally, a thick layer of mucus protects the stomach lining from the effect of its digestive juices.
No single cause has been found for ulcers. However, it is now clear that an ulcer is created by an imbalance, or unevenness, between the digestive fluids hydrochloric acid and pepsin (a digestive enzyme) in the stomach and duodenum.
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